Ultrasound monitoring of experimental ethanol injection into pig liver
| Autor: | M. Taavitsainen, Erna Tapani, Tapio Vehmas |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Pathology
medicine.medical_specialty Swine medicine.medical_treatment Antineoplastic Agents Dissection (medical) Ethanol Injection In Vitro Techniques Administration Cutaneous Injection site Confidence Intervals medicine Animals Radiology Nuclear Medicine and imaging Coloring Agents Ultrasonography Dose-Response Relationship Drug Ethanol business.industry Ultrasound medicine.disease Methylene Blue Dose–response relationship Liver Regression Analysis Percutaneous ethanol injection business Pig liver Extravasation of Diagnostic and Therapeutic Materials |
| Zdroj: | Academic Radiology. 1:21-24 |
| ISSN: | 1076-6332 |
| DOI: | 10.1016/s1076-6332(05)80778-0 |
| Popis: | Rationale and Objectives. In percutaneous ethanol injection therapy, uncontrolled spread of ethanol sometimes causes complications. This study tested the accuracy of ultrasonography in showing the spread of ethanol during injection in normal postmortem pig livers. Methods. Methylene blue-stained 96% (vol) ethanol (0.5–2 ml) was injected into pig livers under sonographic control. The volumes of the sonographically determined areas infiltrated by the injections and the corresponding pale lesions seen after dissecting the livers were measured and compared. The locations of the stained areas were determined. Results. Uncontrolled spread of ethanol was often seen sonographically as hyperechoic lines spreading centrifugally from the injection site. After dissection, nearly all vessels and ducts were stained blue, indicating a major escape of ethanol from the injection sites. The volumes of the sonographically determined injection areas were significantly larger (P Conclusions. Ultrasonography may overestimate the spread of ethanol, making the survival of peripheral tumor cells possible. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|