Supplemental Materials from Clinical Relevance of KRAS-Mutated Subclones Detected with Picodroplet Digital PCR in Advanced Colorectal Cancer Treated with Anti-EGFR Therapy

Autor: Valerie Taly, J. Brian Hutchison, Valérie Boige, Bruno Landi, Jean-François Emile, Olivier Bouché, Darren R. Link, Xinyu Li, Zakaria El Harrak, Thevy Hor, Delphine Le Corre, Preethi Srinivasan, Jeff Olson, Rachel Rowell, Karla Perez-Toralla, Philippe Nizard, Steve K. Kotsopoulos, Corinne Normand, Deniz Pekin, Pierre Laurent-Puig
Rok vydání: 2023
DOI: 10.1158/1078-0432.22460850.v1
Popis: Supplemental Materials. Supplemental Table 1: Patient mutational status and agreement between qPCR, dPCR and sequencing results. Supplemental Table 2: Analysis of different tissue samples coming from the same patient. Supplemental Figure 1: Fraction of mutated alleles (including multiple subclones) in the patients detected by both conventional and droplet-digital PCR procedures. Supplemental Figure 2: Fraction of mutated DNA observed for the different tested mutations of KRAS and BRAF.
Databáze: OpenAIRE