High Diversity of HIV Type 1 in Algeria
| Autor: | Isabelle Garrigue, Patricia Recordon-Pinson, Achour Amrane, Salima Bouzeghoub, El-Hadj Belabbes, Hervé Fleury, Valérie Jauvin |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Adolescent Genes Viral Research methodology media_common.quotation_subject Immunology Human immunodeficiency virus (HIV) HIV Infections Drug resistance medicine.disease_cause Virus Health services HIV Protease Species Specificity Virology Prevalence medicine Humans Child Phylogeny media_common Molecular Epidemiology biology Phylogenetic tree Sequence Analysis RNA business.industry Genetic Variation Middle Aged Viral Load biology.organism_classification HIV Reverse Transcriptase Infectious Diseases Algeria Child Preschool Lentivirus HIV-1 RNA Viral Female business Diversity (politics) |
| Zdroj: | AIDS Research and Human Retroviruses. 22:367-372 |
| ISSN: | 1931-8405 0889-2229 |
| DOI: | 10.1089/aid.2006.22.367 |
| Popis: | We have sequenced different genes of HIV-1 strains from infected individuals recruited in various geographic parts of Algeria; phylogenetic trees were constructed yielding molecular characterization of these strains. Subtype B accounts for 56% of the samples studied and is therefore the predominant subtype, particularly in the north part of the country; but there is a high diversity of the virus including CRF02_AG, CRF06_cpx, CRF02/CRF06 interrecombinants, and different other intersubtype and/or inter-CRF recombinants. The prevalence of these non-B viruses increases in the south part of Algeria that borders sub-Saharan African countries. The high diversity of HIV-1 in Algeria has implications for virological follow-up, resistance surveys, and vaccine design. |
| Databáze: | OpenAIRE |
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