Influence of gender, age and residence altitude on haemoglobin levels and the prevalence of anaemia
| Autor: | Laura Rivilla-Marugán, José Antonio García-Erce, Teófilo Lorente-Aznar |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Multivariate analysis Anemia Population Haemoglobin levels 03 medical and health sciences Hemoglobins 0302 clinical medicine Altitude Sex Factors Residence Characteristics medicine Prevalence Humans 030212 general & internal medicine Overdiagnosis education education.field_of_study business.industry Age Factors Mean age Middle Aged medicine.disease Cross-Sectional Studies Spain Residence Female business Demography |
| Zdroj: | Medicina clinica. 153(11) |
| ISSN: | 1578-8989 |
| Popis: | Introduction There are gaps in our knowledge of the normative levels of haemoglobin and the prevalence of anaemia in our geographical area, and in certain population subgroups. Objectives To study the mean values of haemoglobin in a mountainous Spanish region, according to sex, age range and residence altitude, and the prediction of anaemia according to the WHO thresholds and other proposals. Material and methods Cross-sectional descriptive study of all patients aged >14 residents in the Huesca healthcare Sector with ≥1 laboratory report in the 5 years of inclusion; multivariate analysis to determine the influence of demographic factors on haemoglobin values. Results 583,856 laboratory reports of 90,800 patients (coverage 89.1%) residing between 281 and 1305 m: 54.6% female; mean age 52.6 years. Hb mean: 14.1 g/dl (males: 15.0/females: 13.4). Prevalence of anaemia: 8.99% (males: 7.8%/females: 10.0%). It was more frequent in women (1.6 times) and increased markedly with age: >65 years: 16.5%; ≥75 years: 21.7%; ≥80 years: 25.7%; >90 years 35%. It increased 1.02 times per year, and 0.99 times per metre of altitude. In residents ≥1000 m, anaemia prevalence fell by half. Conclusions We obtained data from sub-populations that were previously not well described; anaemia in the elderly requires consideration. The influence of altitude does not seem to be fully considered within the correction framework proposed by WHO. Broader studies should be planned in order to obtain adequate parameters for the elderly and residents at high altitudes in Spain, as both groups represent an important proportion of the population, to avoid potential underdiagnosis of anaemia and overdiagnosis of other pathologies. |
| Databáze: | OpenAIRE |
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