Fatal Subacute Hepatic Failure in a Patient with AA-Type Amyloidosis: Case Report

Autor: Fayaz A. Handoo, Khaled O. Alsaad, Adel Gublan, Ibrahim Altraif
Rok vydání: 2010
Předmět:
Zdroj: Pathology Research International, Vol 2010 (2010)
Pathology Research International
ISSN: 2042-003X
DOI: 10.4061/2010/648089
Popis: Although systemic amyloidosis of amyloid-associated protein (AA) type (secondary or reactive amyloidosis) frequently involves the liver, it rarely causes clinically apparent liver disease. Mild elevation of alkaline phosphatase and hepatomegaly are the most common biochemical and clinical findings, respectively. We report a case of systemic amyloidosis of AA type, which clinically presented as subacute hepatic failure and resulted in a fatal clinical course in a 69-year-old man. To the best of our knowledge, this is the fifth case of hepatic amyloidosis of AA type that clinically presented as fatal subacute hepatic failure, an unusual clinical presentation for hepatic involvement by systemic AA-type amyloid.
Databáze: OpenAIRE