Anaesthetic Approach for Patient with Hereditary Angioedema
| Autor: | Alyne Andrade Lima, Rafaela Souto e Souza, Maize Cordeiro Melo, Walkiria Wingester Vilas Boas, Marcos Daniel de Faria |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
C1 complement inhibitory protein
business.industry General Anaesthesia medicine.medical_treatment Case Report Disease medicine.disease Intensive care unit hereditary angioedema law.invention Anaesthesia medicine.anatomical_structure Rescue therapy law Submucosa Anesthesia Hereditary angioedema medicine Cholecystectomy Respiratory system business Asthma |
| Zdroj: | Turkish Journal of Anaesthesiology and Reanimation |
| ISSN: | 2667-6370 2667-677X |
| Popis: | Hereditary Angioedema (HEA), a disease caused by a mutation in the gene that encodes for the production of the fraction C1 in the complement (C1-INH), is a rare pathology (1/50.000) that causes swelling of the skin and submucosa in various organs, either naturally triggered or provoked by physical and psychological traumas, infections, or by the use of nonsteroidal anti-inflammatory drugs (NSAIDs) and angiotensin-converting enzyme inhibitors (ACEIs). Surgical trauma may spur the HEA crisis, leading to complications such as the swelling of the respiratory tracts and hemodynamic instability. Thus, the pre-surgical approach to HEA patients requires a specific plan that ensures short term prophylaxis, careful intra-operative management, rescue therapy and intensive post-surgery care. We present a report on a video-laparoscopic cholecystectomy approach for a 28-year-old woman diagnosed with asthma and HEA with symptomatic choledocholithiasis. We opted for short-term prophylaxis and immunology with the intravenous application of C1-INH. Ultrasonography imaging showed arterial wall oedema, which could correspond to a manifestation of C1-INH deficiency in the wall of the manipulated arteries during ultrasonography-guided puncture. Once the patient recovered consciousness, she was transferred to the intensive care unit and was discharged on the 6th day of hospitalisation. |
| Databáze: | OpenAIRE |
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