Abnormal fundus autofluorescence patterns in myopic choroidal neovascularisation
| Autor: | Kaori Sayanagi, Fumi Gomi, Miki Sawa, Yasuo Tano, Hirokazu Sakaguchi, Motokazu Tsujikawa, Yasushi Ikuno |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty Refractive error genetic structures Eye disease Fundus (eye) Vision disorder Cellular and Molecular Neuroscience Ophthalmology Myopia Humans Medicine Fluorescein Angiography Aged Retrospective Studies Aged 80 and over business.industry Age Factors Middle Aged medicine.disease Choroidal Neovascularization eye diseases Sensory Systems Fundus autofluorescence Optic Atrophy medicine.anatomical_structure Choroidal neovascularization Myopic choroidal neovascularisation Disease Progression Female sense organs Choroid medicine.symptom business |
| Zdroj: | British Journal of Ophthalmology. 92:1236-1240 |
| ISSN: | 0007-1161 |
| Popis: | Background/aims: To investigate fundus autofluorescence (FAF) findings in eyes with myopic choroidal neovascularisation (CNV). Methods: Observational case series. Twenty-seven consecutive eyes with CNV for at least 1 year were included. FAF patterns, time after the onset of CNV seen on FAF and FAF changes were evaluated. Results: The following patterns were observed: pattern I (n = 2), relative hypoautofluorescence around the CNV surrounded by hyperautofluorescence a mean of 17 months after CNV onset; pattern II (n = 11), small lobular or multilobular well-defined FAF defects within a relatively hypoautofluorescent region surrounded by hyperautofluorescence a mean of 35 months after onset; pattern III (n = 4), large lobular or multilobular well-defined FAF defects surrounded by hyperautofluorescence a mean of 59 months after onset; and pattern IV (n = 10), large lobular or crescent-shaped well-defined FAF defects a mean of 107 months after onset. Well-defined FAF defects corresponded to chorioretinal atrophy on colour fundus photographs. During the follow-up period, two eyes with pattern I evolved into pattern II. Lobular or multilobular well-defined FAF defects enlarged in 11 eyes (pattern II, nine eyes; pattern III, two eyes). Conclusion: Autofluorescent changes progress over time through pattern grading. A pattern classification might be helpful to predict chorioretinal atrophy changes around myopic CNV. |
| Databáze: | OpenAIRE |
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