Epidemiology of soil transmitted helminth and Strongyloides stercoralis infections in remote rural villages of Ranomafana National Park, Madagascar
| Autor: | Koeun Choi, Patricia C. Wright, Small Pm, Rado Rakotoarison, Paul Castle, Ivan Crnosija, Luis A. Marcos, Simon Grandjean Lapierre, Inès Vigan-Womas, Lee Hakami, Emma Rakotomalala, Anjanirina Rahantamalala, Jaydon Kiernan |
|---|---|
| Přispěvatelé: | Stony Brook University [SUNY] (SBU), State University of New York (SUNY), Unité d'immunologie des maladies infectieuses [Antananarivo, Madagascar] (IPM), Institut Pasteur de Madagascar, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), David E. Rogers Student Fellowship Award, Martin and Dorothy Spatz Foundation, and support from the Global Health Institute of Stony Brook University and the Institut Pasteur de Madagascar., We would like to acknowledge all the villagers who participated in this study. We are grateful to the Centre ValBio team and the health team, including Maya Moore, Pascal Rabeson, Jesse McKinney, Miarintsoa Fara Nantenaina Rakotoarison, Andry Andriamiadanarivo, Fara Maria Violette Nambinintsoa and Francis Daniel Lovasoa, for their valuable support in translating, field logistics, sample collection and overall support. We also thank MICET (Malagasy Institute for the Conservation of Tropical Environments) for their logistical support. |
| Rok vydání: | 2019 |
| Předmět: |
Ancylostomatoidea
Rural Population 0301 basic medicine Parks Recreational Ifanadiana Ranomafana Feces 0302 clinical medicine Risk Factors Surveys and Questionnaires Epidemiology Prevalence Ascariasis biology National park Age Factors General Medicine 3. Good health Trichuris [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology Infectious Diseases Geography Strongyloidiasis Neglected tropical diseases [SDV.IMM]Life Sciences [q-bio]/Immunology Soil-transmitted helminth medicine.medical_specialty Short Communication 030106 microbiology 030231 tropical medicine [SDV.BC]Life Sciences [q-bio]/Cellular Biology intestinal parasites Microbiology Education Strongyloides stercoralis Hookworm Infections 03 medical and health sciences Environmental health parasitic diseases Madagascar medicine Animals Humans Helminths Trichuriasis Ascaris lumbricoides Public Health Environmental and Occupational Health [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biology biology.organism_classification [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie Parasitology |
| Zdroj: | Pathogens and Global Health Pathogens and Global Health, Taylor & Francis, 2019, 113 (2), pp.94-100. ⟨10.1080/20477724.2019.1589927⟩ |
| ISSN: | 2047-7732 2047-7724 |
| DOI: | 10.1080/20477724.2019.1589927 |
| Popis: | International audience; Soil-transmitted helminth (STH) infections carry the highest number of disability adjusted life years among all neglected tropical diseases, disproportionately affecting low-income countries such as Madagascar. This study describes the epidemiology of STH and S. stercoralis infections in twelve remote villages surrounding Ranomafana National Park (RNP), Ifanadiana, Madagascar. Questionnaires and stool samples were collected from 574 subjects from random households. The Kato-Katz method and spontaneous sedimentation technique were used to examine stool samples for evidence of infection. Infection prevalence rates were 71.4% for Ascaris lumbricoides (95% CI: 67.7–75.1), 74.7% for Trichuris trichiura (95% CI: 71.1–78.2), 33.1% for hookworm (95% CI: 29.2–36.9), and 3.3% for Strongyloides stercoralis (95% CI: 1.84–4.77). Participants who were older in age (OR = 0.96; 95% CI: 0.95–0.99) and who had a high school education (OR = 0.17; 95% CI: 0.04–0.77) were less likely to be infected with a STH. Females were less likely to be infected with A. lumbricoides (OR = 0.52; 95% CI: 0.33–0.82). Participants living in villages further from the main road were more likely to be infected with a STH (F = 4.00, p = 0.02). Overall, this study found that 92.5% (95% CI: 90.3–94.6) of the people living in rural regions near RNP have at least one STH infection. This calls into question the current preventative chemotherapy (PC) program in place and suggests that further medical, socioeconomic, and infrastructural deveopments are needed to reduce STH prevalence rates among this underserved population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|