Relationship of adrenergic and electrical brain stimulation induced feeding responses
| Autor: | Sarah F. Leibowitz, Jacqueline Carter, Taro J. Adachi, Ronnie Halperin, Christine L. Gatchalian |
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| Rok vydání: | 1983 |
| Předmět: |
Male
medicine.medical_specialty Adrenergic receptor Clinical Biochemistry Hypothalamus Hypothalamus Middle Adrenergic Stimulation Toxicology Biochemistry Eating Norepinephrine Behavioral Neuroscience Phentolamine Internal medicine Reaction Time medicine Animals Biological Psychiatry Pharmacology business.industry digestive oral and skin physiology Rats Inbred Strains Electric Stimulation Rats Receptors Adrenergic Endocrinology Brain stimulation Brain stimulation reward business Electrical brain stimulation Paraventricular Hypothalamic Nucleus medicine.drug |
| Zdroj: | Pharmacology Biochemistry and Behavior. 18:415-422 |
| ISSN: | 0091-3057 |
| DOI: | 10.1016/0091-3057(83)90464-1 |
| Popis: | Electrical and adrenergic brain stimulation can induce eating in satiated animals. This report explores the interrelationship of brain feeding systems mediating eating in response to norepinephrine and electrical stimulation of the hypothalamus in rats. It was found that simultaneous adrenergic and electrical brain stimulation resulted in a significant increase in food intake as compared to each stimulation condition alone. Furthermore, pharmacological blockade of the alpha-adrenergic receptors in the hypothalamus attenuated feeding in response to adrenergic, but not electrical brain stimulation. Results are interpreted to suggest that these feeding systems are independent at the level of the diencephalon. The role of the vagus nerve as an efferent link through which these brain systems may influence feeding behavior is discussed. |
| Databáze: | OpenAIRE |
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