Potential Effect of Post-Transcriptional Substitutions of Tyrosine for Cysteine Residues on Transformation of Amyloidogenic Proteins
Autor: | Vladimir I. Muronetz, Denis V. Pozdyshev, Maria V. Medvedeva, Irina A. Sevostyanova |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Biochemistry (Moscow). 87:170-178 |
ISSN: | 1608-3040 0006-2979 |
Popis: | The review considers the reasons and consequences of post-transcriptional tyrosine substitutions for cysteine residues. Main attention is paid to the Tyr/Cys substitutions that arise during gene expression in bacterial systems at the stage of protein translation as a result of misrecognition of the similar mRNA codons. Notably, translation errors generally occur relatively rarely - from 10 |
Databáze: | OpenAIRE |
Externí odkaz: | |
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