Potential Effect of Post-Transcriptional Substitutions of Tyrosine for Cysteine Residues on Transformation of Amyloidogenic Proteins

Autor: Vladimir I. Muronetz, Denis V. Pozdyshev, Maria V. Medvedeva, Irina A. Sevostyanova
Rok vydání: 2022
Předmět:
Zdroj: Biochemistry (Moscow). 87:170-178
ISSN: 1608-3040
0006-2979
Popis: The review considers the reasons and consequences of post-transcriptional tyrosine substitutions for cysteine residues. Main attention is paid to the Tyr/Cys substitutions that arise during gene expression in bacterial systems at the stage of protein translation as a result of misrecognition of the similar mRNA codons. Notably, translation errors generally occur relatively rarely - from 10
Databáze: OpenAIRE
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