Effects of tobacco smoke extracts on collagen biosynthesis by fibroblast cell cultures

Autor: Marc Hivert, Annette Chamson, Jacques Frey
Rok vydání: 1982
Předmět:
Zdroj: Journal of Toxicology and Environmental Health. 9:921-932
ISSN: 0098-4108
DOI: 10.1080/15287398209530214
Popis: The effects of tobacco smoke extracts on collagen and total protein synthesis by fibro‐blast cell cultures were studied. Tobacco extract with a nicotine concentration of 35 nmol per milliliter of culture medium increased collagen production but not protein secretion in the culture medium. Not only the rate of collagen synthesis but also the types of collagen produced were affected; in particular, there was a decrease of type III collagen.
Databáze: OpenAIRE