Rings and double minutes in a case with blastic phase of chronic myelocytic leukemia
| Autor: | Masahide Kamakura, Mariko Uehara, Mitsushiro Kida |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Adult
Cancer Research medicine.medical_specialty Abnormal chromosomes Blastic Phase Biology Bone Marrow Genetics medicine Humans Philadelphia Chromosome Ring Chromosomes Molecular Biology Chromosome Aberrations Cytogenetics Karyotype Molecular biology Double ring medicine.anatomical_structure Leukemia Myeloid Karyotyping Female Myelocytic leukemia Bone marrow Blast Crisis Busulfan medicine.drug |
| Zdroj: | Cancer Genetics and Cytogenetics. 25:253-258 |
| ISSN: | 0165-4608 |
| DOI: | 10.1016/0165-4608(87)90185-3 |
| Popis: | The patient studied was a 33-year-old female in the blastic phase of chronic myelocytic leukemia resistant to busulfan. The results of cytogenetic studies of bone marrow cells were as follows: The abnormal chromosomes were double Ph 1 ,+19,+6,+B, ring D, double ring D, double minutes (DM) of various sizes, etc. The mean number of DM per cell was increased in 4-day culture compared with that in 1-day culture. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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