Popis: |
The amino acid sequence of pelamitoxin a, the main neurotoxin of the sea snake, Pelamis platurus , has been completed. Analysis was done principally by means of Edman degradation of constituent tryptic peptides; chymotryptic and thermolytic peptides were also studied to assist in the sequence alignment. The results indicate that pelamitoxin a is identical to schistosa toxin 5 in amino acid sequence. These results indicate the feasibility of producing a common antivenin against toxins from some of the most common sea snakes. |