Amino acid sequence of pelamitoxin a, the main neurotoxin of the sea snake, Pelamis platurus

Autor: R.Q. Blackwell, Y.O. Hung, Chung-Li Wang, C.S. Liu
Rok vydání: 1976
Předmět:
Zdroj: Toxicon. 14:459-466
ISSN: 0041-0101
DOI: 10.1016/0041-0101(76)90063-5
Popis: The amino acid sequence of pelamitoxin a, the main neurotoxin of the sea snake, Pelamis platurus , has been completed. Analysis was done principally by means of Edman degradation of constituent tryptic peptides; chymotryptic and thermolytic peptides were also studied to assist in the sequence alignment. The results indicate that pelamitoxin a is identical to schistosa toxin 5 in amino acid sequence. These results indicate the feasibility of producing a common antivenin against toxins from some of the most common sea snakes.
Databáze: OpenAIRE