Efficient two-photon luminescence for cellular imaging using biocompatible nitrogen-doped graphene quantum dots conjugated with polymers

Autor: Jiu Yao Wang, Wen Shuo Kuo, Chih Li Lilian Hsu, Jui-Cheng Chang, Kun Lin Yang, Ting Mao Chou, Chia Yuan Chang, Shih Yao Chen, Ping Ching Wu, Wen Lung Wang, Chia Hung Huang
Rok vydání: 2017
Předmět:
Zdroj: Nanoscale. 10(1)
ISSN: 2040-3372
Popis: Nitrogen-doped graphene quantum dot (N-GQD) nanomaterials conjugated with polyethylenimine (PEI)-polystyrene sulfonate (PSS)-anti-epidermal growth factor receptor (AbEGFR) antibody (N-GQD-PEI-PSS-AbEGFR) demonstrated impressive two-photon properties and stability, signifying that they can serve as an effective two-photon contrast agent in two-photon bioimaging. Furthermore, they provided high intensity, brightness, and signal-to-noise ratios at an ultra-low two-photon excitation (TPE) power level in an observation extending to a deep, three-dimensional depth.
Databáze: OpenAIRE