A prospective histomorphometric and cephalometric comparison of bovine bone substitute and autogenous bone grafting in Le Fort I osteotomies
| Autor: | Ulrich Schwarz, Bassem Ahmed Bayazeed, Siegmar Reinert, Rainer Schmelzeisen, Heiner Nagursky, Andreas Naros, Sebastian Sauerbier |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Adolescent Cephalometry medicine.medical_treatment Orthognathic surgery Connective tissue Dentistry Bone grafting Iliac crest Ilium 03 medical and health sciences Young Adult 0302 clinical medicine Osteogenesis medicine Maxilla Animals Humans Osteotomy Le Fort Prospective Studies Bridge (dentistry) Bone regeneration Minerals Bone Transplantation business.industry 030206 dentistry Middle Aged Grafting medicine.anatomical_structure Otorhinolaryngology Trephine 030220 oncology & carcinogenesis Bone Substitutes Surgery Cattle Female Oral Surgery business |
| Zdroj: | Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 47(2) |
| ISSN: | 1878-4119 |
| Popis: | Purpose The aim of the present study was the histomorphometric and cephalometric comparison of autogenous bone grafting of the anterior iliac crest and the application of bovine bone substitute concerning new bone formation and postoperative stability in patients undergoing orthognathic Le Fort I osteotomy. Patients and methods Twenty-five patients requiring orthognathic surgery with Le Fort I osteotomy were included in this study. Patients were randomly divided into three groups receiving either autogenous iliac crest BONE grafting (BONE; n = 8) or xenogenic bovine bone grafting (Bio-Oss®) in INTER (n = 12) or in ONLAY (n = 5) position. Histomorphometric analysis was performed using trephine bone biopsies from the autogenous, respectively xenogenic bone grafting region. Postoperative stability was evaluated using teleradiographies of three different timepoints. Results All groups showed comparable mineralized fractions in bone biopsies of 50.2% (±13.2%) INTER, 46.48% (±12.3%) ONLAY and 57.1% (±20.6%) BONE as well as comparable percentage of connective tissue. Patients in the INTER-group revealed the lowest relapse rate of 20.5% (INTER) compared to 30.3% (ONLAY) and 33.0% (BONE). All groups underwent comparable maxillary advancement and healing time. Conclusions Present results indicate that block shaped bovine bone substitute is a promising alternative to autogenous bone grafting to bridge the Le Fort I osteotomy gap in orthognathic surgery. |
| Databáze: | OpenAIRE |
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