AuCl3-Catalyzed Hemiacetal Activation for the Stereoselective Synthesis of 2-Deoxy Trehalose Derivatives
| Autor: | Robin Jeanneret, Carlo Walz, Maarten van Meerbeek, Sarah Coppock, M. Carmen Galan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Jeanneret, R, Walz, C, van Meerbeek, M, Coppock, S & Galan, M C 2022, ' AuCl3-Catalyzed Hemiacetal Activation for the Stereoselective Synthesis of 2-Deoxy Trehalose Derivatives ', Organic Letters, vol. 24, no. 34, pp. 6304-6309 . https://doi.org/10.1021/acs.orglett.2c02530 |
| Popis: | A new practical, catalytic, and highly stereoselective method for directly accessing 1,1-α,α'-linked 2-deoxy trehalose analogues via AuCl 3-catalyzed dehydrative glycosylation using hemiacetal glycosyl donors and acceptors is described. The method relies on the chemoselective Brønsted acid-type activation of tribenzylated 2-deoxy hemiacetals in the presence of other less reactive hemiacetals. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|