Additional file 3 of Unveiling role of sphingosine-1-phosphate receptor 2 as a brake of epithelial stem cell proliferation and a tumor suppressor in colorectal cancer

Autor: Petti, Luciana, Rizzo, Giulia, Rubbino, Federica, Sudharshan Elangovan, Colombo, Piergiuseppe, Restelli, Silvia, Piontini, Andrea, Arena, Vincenzo, Carvello, Michele, Romano, Barbara, Cavalleri, Tommaso, Anselmo, Achille, Ungaro, Federica, D’Alessio, Silvia, Spinelli, Antonino, Stifter, Sanja, Grizzi, Fabio, Sgambato, Alessandro, Danese, Silvio, Laghi, Luigi, Malesci, Alberto, Vetrano, Stefania
Rok vydání: 2021
DOI: 10.6084/m9.figshare.14433176
Popis: Additional file 3: Supplementary Figure 3. Analysis of survival rate of the colonic mucosa of S1PR2−/− and S1PR2+/+ mice after AOM/DSS induced colitis-associated cancer. The tissues (healthy and tumor regions) were evaluated by immunohistochemical analysis with an anti-cleaved caspase-3 antibody. The images were acquired by the DotSlide system at 20x objective. Apoptotic cells (blue arrows) were examined microscopically at 40X magnification. Data are presented as the mean ± SEM, and significance was evaluated by the Mann-Whitney test. Data is representative of 2 experiments (n = 6).
Databáze: OpenAIRE