Effects of Helichrysum italicum extract on growth and enzymatic activity of Staphylococcus aureus
Autor: | Giuseppe Bisignano, M.A. Cannatelli, Maria Paola Germanò, Antonia Nostro, Giuseppe Crisafi, V. Alonzo |
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Rok vydání: | 2001 |
Předmět: |
Microbiology (medical)
Coagulase Staphylococcus aureus Micrococcaceae Inhibition Helichrysum italicum MRSA MSSA Growth Enzymatic activity Virulence Biology Pharmacognosy Asteraceae In Vitro Techniques medicine.disease_cause Microbiology medicine Humans Micrococcal Nuclease Pharmacology (medical) Enzyme Inhibitors Antibacterial agent Deoxyribonucleases Plants Medicinal Plant Extracts General Medicine Lipase Antimicrobial biology.organism_classification Anti-Bacterial Agents Infectious Diseases |
Zdroj: | International journal of antimicrobial agents. 17(6) |
ISSN: | 0924-8579 |
Popis: | Helichrysum italicum G. Don (Compositae) is a shrub commonly found in dry, sandy and stony areas of Mediterranean regions. This plant is known for its anti-inflammatory, anti-allergic and antimicrobial activity. The aim of this study was to evaluate the effect of the diethyl ether extract on growth of Staphylococcus aureus (ATCC 6538P, MRSA and MSSA isolates) and the influence of subminimum inhibitory concentrations (subMICs) on some enzymes which are considered virulence factors. The results indicate that the H. italicum extract had an inhibitory effect on S. aureus strains reducing both their growth and some of the enzymes such as coagulase, DNAse, thermonuclease and lipase. Helichrysum italicum extract could be a novel antimicrobial agent, less toxic to human skin and tissues, worthy of further studies. |
Databáze: | OpenAIRE |
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