TelomereHunter: telomere content estimation and characterization from whole genome sequencing data

Autor: Ivo Buchhalter, Lars Feuerbach, Philip Ginsbach, Karsten Rippe, Barbara Hutter, Peter Lichter, Benedikt Brors, David T.W. Jones, Paul A. Northcott, Lina Sieverling, Stefan M. Pfister, Katharina I. Deeg
Rok vydání: 2016
Předmět:
Popis: Summary:Telomere shortening plays an important role in cellular aging and tumor suppression. The availability of large next-generation sequencing cohorts of matched tumor and control samples enables a computational high-throughput analysis of changes in telomere content and composition in cancer. Here we describe a novel software tool specifically tailored for the processing of large data collections.Availability and Implementation:TelomereHunter is implemented as a python package. It is freely available online at: http://www.dkfz.de/en/applied-bioinformatics/telomerehunter/telomerehunter.html.
Databáze: OpenAIRE