Polyphenols delivery by polymeric materials: challenges in cancer treatment

Autor:	Manuela Curcio, Orazio Vittorio, Anna Dubrovska, Francesca Iemma, Monica Cojoc, Silke Hampel, Gerardo F. Goya, Giuseppe Cirillo
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	Materials science Polymers Pharmaceutical Science Nanotechnology 02 engineering and technology Review Review Article RM1-950 03 medical and health sciences 0302 clinical medicine Neoplasms Animals Humans polyphenols Drug Carriers food and beverages polymeric materials General Medicine 021001 nanoscience & nanotechnology Cancer treatment 030220 oncology & carcinogenesis Nanocarrier Nanoparticles nanocarrier cancer therapy Biochemical engineering Therapeutics. Pharmacology 0210 nano-technology
Zdroj:	Drug Delivery, Vol 24, Iss 1, Pp 162-180 (2017) Drug Delivery article-version (VoR) Version of Record Drug Delivery 24(2017)1, 162-180
ISSN:	1521-0464 1071-7544
Popis:	Nanotechnology can offer different solutions for enhancing the therapeutic efficiency of polyphenols, a class of natural products widely explored for a potential applicability for the treatment of different diseases including cancer. While possessing interesting anticancer properties, polyphenols suffer from low stability and unfavorable pharmacokinetics, and thus suitable carriers are required when planning a therapeutic protocol. In the present review, an overview of the different strategies based on polymeric materials is presented, with the aim to highlight the strengths and the weaknesses of each approach and offer a platform of ideas for researchers working in the field.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0dfa3ecb717c7647e48bdb0b411858 https://doaj.org/article/304f00f918754e25989ab20d876dc6ce Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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