Discrepant Results of Adrenal Venous Sampling in Seven Patients with Primary Aldosteronism
| Autor: | Martin Mašek, M Kasalický, Robert Holaj, Ján Rosa, Jana Dvořáková, Tomáš Zelinka, Jana Vlková, Branislav Štrauch, David Michalský, Ondřej Petrák, Jiří Widimský |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male endocrine system medicine.medical_specialty High selectivity chemistry.chemical_compound Primary aldosteronism Internal medicine Adrenal Glands Hyperaldosteronism medicine Humans Aged Blood Specimen Collection Catheter insertion Aldosterone business.industry General Medicine Middle Aged medicine.disease Adrenal venous sampling Anomalous venous drainage Endocrinology chemistry Nephrology Cardiology Adrenal veins Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Kidney and Blood Pressure Research. 35:205-210 |
| ISSN: | 1423-0143 1420-4096 |
| DOI: | 10.1159/000330720 |
| Popis: | Background: Adrenal venous sampling serves as a discrimination between uni- and bilateral forms of primary aldosteronism (PA). Even correctly performed adrenal venous sampling may lead to non-diagnostic results in some cases. Results: We describe 7 subjects with PA in whom correct cannulation of adrenal veins (high selectivity index defined as cortisol(adrenal)/cortisol(periphery) ratio) was associated with aldosterone (ALDO) suppression (ALDO/cortisol(adrenal)/ALDO/cortisol(periphery) ratio (right)/ALDO/cortisol(left) 1.78). Conclusions: Our results document some uncertainties in interpreting results of adrenal venous sampling in subjects with PA which may result from deep catheter insertion, anomalous venous drainage, or fluctuations in ALDO secretion. |
| Databáze: | OpenAIRE |
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