Autor: |
Xi-Fan He, Hui Wang, Ye Tian, Te Zhang, Zhi-Peng Qiu, Xiao-Jiao Cui, Jing-Sha Zhou, Xin-Lan Yan, Yi-Wei Wu, Yi-Sha Pan, Yang-Bo Ning, Lin Chen, Kun-Lun Zhang, Wei-Hao Zhao, David Sharma, Xiao-Dan Tan, Michael Bo Zhang |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
Biological trace element research. |
ISSN: |
1559-0720 |
Popis: |
Dental calculus is a potential material that can be used for assessing chronic exposure to trace heavy metals in oral cavity as it is a long-term reservoir. The aim of this study was to investigate the correlation between dental calculus copper levels and risk of oral submucous fibrosis (OSF) due to chewing dried areca-nut quids in Mainland China. This study included 34 OSF (grade 1) sufferers with dried areca-nut quids chewing as the patient group and 23 healthy individuals without areca-nut chewing as the control group. The dental calculus sample was obtained from all 57 participants and evaluated by inductively coupled plasma mass spectrometry (ICP-MS) for dental calculus level of copper. This work revealed that the mean copper level of dental calculus was significantly higher in OSF (grade 1) sufferers with areca-nut chewing than those in healthy individuals without areca-nut chewing (p 0.001). This work provided an evidence to support that there may be a positive correlation between elevated levels of copper in dental calculus caused by chewing dried areca-nut quids and an increased risk of developing OSF in Mainland China. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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