In situ effect of a proanthocyanidin mouthrinse on dentin subjected to erosion

Autor: F. Cardoso, Ana Paula Boteon, Linda Wang, Heitor Marques Honório, Anuradha Prakki, Tamires Alves Pereira da Silva
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Applied Oral Science, Vol 28 (2020)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Journal of Applied Oral Science v.28 2020
Journal of applied oral science
Journal of Applied Oral Science, Volume: 28, Article number: e20200051, Published: 23 OCT 2020
ISSN: 1678-7765
Popis: Proanthocyanidin has been shown to be efficient in inhibiting matrix metalloproteinases. Objective The aim of this in situ study was to evaluate the protective effect of Proanthocyanidin-based mouthrinses either with naturally acidic or with a neutral pH applied on dentin subjected to erosion. Methodology Eight volunteers wore one palatal device in two phases (7 days washout) with 16 samples per group (n=8). The groups under study were: First Phase/ G1 – 10% proanthocyanidin mouthrinse (pH 7.0, Experimental group 1 – Purified Grape Seeds Oligomeric Proanthocyanidins), G2 – 10% proanthocyanidin mouthrinse (pH 3.0, Experimental group 2 – Purified Grape Seeds Oligomeric Proanthocyanidins). Second Phase/ G3 – 0.12% chlorhexidine mouthrinse (pH 7.0, Positive control group), G4 – no previous treatment (Negative control group). Each device was subjected to 3 erosive cycles (5 minutes) per day for 5 days. Treatments with different mouthrinses were applied once after the second erosive challenge (5 minutes). Profilometry was used to quantify dentin loss (µm). Results Data were analyzed by repeated measures of ANOVA followed by Fisher’s test (p
Databáze: OpenAIRE