A cross-over, post-electroconvulsive therapy comparison of clinical recovery from rocuronium versus succinylcholine
| Autor: | Aysegul Yildiz, Erol Gokel, Kemal Sagduyu, Ali Günerli, Necati Gokmen, Leyla Iyilikci, Deniz Cihan Turkkal |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Atropine Male medicine.medical_specialty Time Factors Adolescent medicine.medical_treatment Succinylcholine Hospitals University Young Adult Electroconvulsive therapy Anesthesiology medicine Humans Androstanols Rocuronium Electroconvulsive Therapy Tongue depressor Cross-Over Studies business.industry Parasympatholytics Middle Aged Crossover study Neostigmine Surgery Anesthesiology and Pain Medicine Parasympathomimetics Anesthesia Neuromuscular Depolarizing Agents Injections Intravenous Breathing Female business medicine.drug Neuromuscular Nondepolarizing Agents |
| Zdroj: | Journal of clinical anesthesia. 20(8) |
| ISSN: | 0952-8180 |
| Popis: | Study Objective To evaluate the effect of the neuromuscular blocking agent, rocuronium, on clinical recovery from electroconvulsive therapy (ECT) as compared with succinylcholine. Design Cross-over study. Setting University hospital. Patients 13 ASA physical status I and II patients, ages 18 to 60 years, receiving ECT three times a week. Interventions Each patient received either succinylcholine before the first ECT session (Group S) and rocuronium before the third ECT session (Group R). Muscle paralysis was produced with succinylcholine one mg kg −1 intravenously (IV) or rocuronium 0.3 mg kg −1 IV. Reversal of the residual neuromuscular block (Group R) was accomplished with 10 μg kg −1 of atropine and 20 μg kg −1 of neostigmine after completion of the ECT procedure. Measurements Motor seizure duration time, time to first spontaneous breathing, eye opening, head lift, and tongue depressor test were recorded. Main Result Motor seizure duration and time to first spontaneous breath was longer (33.6 sec vs. 24.2 sec; 9.46 min vs 8.07 min, respectively) in the rocuronium group than the succinylcholine group. No significant difference was detected between the two groups in eye opening, head lift, or tongue depressor testing. Conclusion Rocuronium, when used in conjunction with a reversal agent, may be an adequate alternative to succinylcholine as a neuromuscular blocker during ECT. |
| Databáze: | OpenAIRE |
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