A comparative bio-evaluation and chemical profiles of Calendula officinalis L. extracts prepared via different extraction techniques
Autor: | Kouadio Ibrahime Sinan, Gokhan Zengin, Gunes Ak, Monica Gallo, Marie Carene Nancy Picot-Allain, Mustafa Abdullah Yilmaz, Oguz Cakir, Mohamad Fawzi Mahomoodally, Domenico Montesano, Souheir Bensari |
---|---|
Přispěvatelé: | Dicle Üniversitesi, Çakır, Oğuz, Yilmaz, Mustafa Abdullah, Ak, G., Zengin, G., Sinan, K. I., Mahomoodally, M. F., Picot-Allain, M. C. N., Cakir, O., Bensari, S., Yilmaz, M. A., Gallo, M., Montesano, D. |
Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
0106 biological sciences
cholinesterase Tyrosinase Flavonoid tyrosinase Amentoflavone lcsh:Technology 01 natural sciences lcsh:Chemistry chemistry.chemical_compound Maceration (wine) General Materials Science lcsh:QH301-705.5 Instrumentation Fluid Flow and Transfer Processes chemistry.chemical_classification Maceration biology Traditional medicine lcsh:T 010405 organic chemistry Process Chemistry and Technology Extraction (chemistry) fungi General Engineering food and beverages Cholinesterase maceration biology.organism_classification lcsh:QC1-999 0104 chemical sciences Computer Science Applications lcsh:Biology (General) lcsh:QD1-999 chemistry Phytochemical lcsh:TA1-2040 Calendula officinalis Officinalis marigold lcsh:Engineering (General). Civil engineering (General) Marigold lcsh:Physics 010606 plant biology & botany |
Zdroj: | Applied Sciences Volume 10 Issue 17 Applied Sciences, Vol 10, Iss 5920, p 5920 (2020) |
Popis: | WOS:000569663900001 Calendula officinalis L., (marigold), well known for its medicinal properties, has been extensively studied for its therapeutic properties. Nonetheless, as far as the literature could establish, no study has attempted to comparatively assess the biological (antioxidant and enzyme inhibitory potential) of the flowers, leaves, and roots of C. officinalis extracted using conventional (maceration and Soxhlet extraction (SE)) and non-conventional extraction (homogenizer (HAE) and ultrasound (UAE) assisted extraction) techniques. The detailed phytochemical profile of each extract along with the concentration of specific bioactive compounds has also been established. Total phenolic content was highest for the flower extracts while flavonoid content was highest in the leaf extracts. Phytochemical profiling showed that the extraction method influenced the phytochemical composition of the extract. Nicotiflorin was identified in the flower extracts only while amentoflavone occurred only in the roots, inferring that the occurrence of bioactive compounds varies within a plant. The flower extracts showed highest antioxidant potential while the roots extracts were potent inhibitors of cholinesterase and tyrosinase. This study provides valuable data on the influence of extraction techniques on the recovery of bioactive compounds from plants. In an endeavor to scale-up extraction from plant considering the more efficient extraction method is of paramount importance. Moreover, the study highlighted the necessity to thoroughly examine the biological activities of various parts of a plant obtained via different extraction protocols. |
Databáze: | OpenAIRE |
Externí odkaz: |
Pro tento záznam nejsou dostupné žádné jednotky.