A comparative bio-evaluation and chemical profiles of Calendula officinalis L. extracts prepared via different extraction techniques

Autor: Kouadio Ibrahime Sinan, Gokhan Zengin, Gunes Ak, Monica Gallo, Marie Carene Nancy Picot-Allain, Mustafa Abdullah Yilmaz, Oguz Cakir, Mohamad Fawzi Mahomoodally, Domenico Montesano, Souheir Bensari
Přispěvatelé: Dicle Üniversitesi, Çakır, Oğuz, Yilmaz, Mustafa Abdullah, Ak, G., Zengin, G., Sinan, K. I., Mahomoodally, M. F., Picot-Allain, M. C. N., Cakir, O., Bensari, S., Yilmaz, M. A., Gallo, M., Montesano, D.
Jazyk: angličtina
Rok vydání: 2020
Předmět:
0106 biological sciences
cholinesterase
Tyrosinase
Flavonoid
tyrosinase
Amentoflavone
lcsh:Technology
01 natural sciences
lcsh:Chemistry
chemistry.chemical_compound
Maceration (wine)
General Materials Science
lcsh:QH301-705.5
Instrumentation
Fluid Flow and Transfer Processes
chemistry.chemical_classification
Maceration
biology
Traditional medicine
lcsh:T
010405 organic chemistry
Process Chemistry and Technology
Extraction (chemistry)
fungi
General Engineering
food and beverages
Cholinesterase
maceration
biology.organism_classification
lcsh:QC1-999
0104 chemical sciences
Computer Science Applications
lcsh:Biology (General)
lcsh:QD1-999
chemistry
Phytochemical
lcsh:TA1-2040
Calendula officinalis
Officinalis
marigold
lcsh:Engineering (General). Civil engineering (General)
Marigold
lcsh:Physics
010606 plant biology & botany
Zdroj: Applied Sciences
Volume 10
Issue 17
Applied Sciences, Vol 10, Iss 5920, p 5920 (2020)
Popis: WOS:000569663900001 Calendula officinalis L., (marigold), well known for its medicinal properties, has been extensively studied for its therapeutic properties. Nonetheless, as far as the literature could establish, no study has attempted to comparatively assess the biological (antioxidant and enzyme inhibitory potential) of the flowers, leaves, and roots of C. officinalis extracted using conventional (maceration and Soxhlet extraction (SE)) and non-conventional extraction (homogenizer (HAE) and ultrasound (UAE) assisted extraction) techniques. The detailed phytochemical profile of each extract along with the concentration of specific bioactive compounds has also been established. Total phenolic content was highest for the flower extracts while flavonoid content was highest in the leaf extracts. Phytochemical profiling showed that the extraction method influenced the phytochemical composition of the extract. Nicotiflorin was identified in the flower extracts only while amentoflavone occurred only in the roots, inferring that the occurrence of bioactive compounds varies within a plant. The flower extracts showed highest antioxidant potential while the roots extracts were potent inhibitors of cholinesterase and tyrosinase. This study provides valuable data on the influence of extraction techniques on the recovery of bioactive compounds from plants. In an endeavor to scale-up extraction from plant considering the more efficient extraction method is of paramount importance. Moreover, the study highlighted the necessity to thoroughly examine the biological activities of various parts of a plant obtained via different extraction protocols.
Databáze: OpenAIRE
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