Analgesic effects of detomidine in thoroughbred horses with chronic tendon injury
Autor: | Avril Waterman, A.E. Goodship, J.P. Chambers, A. Livingston |
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Rok vydání: | 1993 |
Předmět: |
Male
Pain Threshold medicine.medical_specialty medicine.drug_class Analgesic Pain Xylazine Tendon Injuries Threshold of pain medicine Noxious stimulus Animals Horses Analgesics Detomidine General Veterinary business.industry Imidazoles Chronic pain medicine.disease Surgery Anesthesia Sedative Morphine Female business medicine.drug |
Zdroj: | Research in Veterinary Science. 54:52-56 |
ISSN: | 0034-5288 |
DOI: | 10.1016/0034-5288(93)90010-d |
Popis: | This study was undertaken to assess the analgesia provided by detomidine (20 μg kg −1 intravenously) in thoroughbred horses. Pain thresholds to a mechanical noxious stimulus were measured before and after a period of mild chronic pain in one foreleg. Detomidine was a good analgesic in control animals; their pain thresholds were significantly elevated for about 60 minutes. After injury, the injured leg had a significantly lower pain threshold and the intensity and duration of analgesia provided by detomidine were significantly reduced. The analgesia in the opposite (sound) leg was also reduced, indicating that there were both central and peripheral aspects to this increased sensitivity to painful stimuli. Detomidine deserves to be considered as a potent analgesic in the horse rather than a sedative with analgesic side effects. |
Databáze: | OpenAIRE |
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