Post-immunotherapy imaging in lung cancer
| Autor: | Mylene T. Truong, Brett W. Carter, Ioannis Vlahos, Mehmet Altan, Myrna C.B. Godoy, Jitesh Ahuja, Chad D. Strange, Girish S. Shroff |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Diagnostic Imaging
Oncology medicine.medical_specialty Lung Neoplasms animal diseases medicine.medical_treatment Immune checkpoint inhibitors chemical and pharmacologic phenomena 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Immune system Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Adverse effect Response criteria Lung cancer Lung business.industry General Medicine Immunotherapy biochemical phenomena metabolism and nutrition medicine.disease Cancer treatment 030220 oncology & carcinogenesis bacteria Non small cell business |
| Zdroj: | Clinical Radiology. 77:44-57 |
| ISSN: | 0009-9260 |
| Popis: | By boosting the immune system, immunotherapy with immune checkpoint inhibitors (ICIs) has altered the management of patients with various cancers including those with metastatic non-small cell lung cancer (NSCLC). As a result of immune system activation, ICIs are associated with unique response patterns (that are not addressed by traditional response criteria) and inflammatory side effects termed immune-related adverse events. In this article, we will review the role of immunotherapy in cancer treatment, specifically ICIs used in NSCLC treatment, radiological response criteria of immunotherapy, and the imaging spectrum of immune-related adverse events. |
| Databáze: | OpenAIRE |
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