Polymer-Coated Magnetite Nanoparticles for Protein Immobilization
| Autor: | Kinga Mylkie, Patryk Rybczynski, Marta Ziegler-Borowska, Pawel Nowak |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
magnetic nanoparticles
Materials science Nanoparticle Nanotechnology Review 02 engineering and technology 010402 general chemistry lcsh:Technology 01 natural sciences chemistry.chemical_compound Magnetite Nanoparticles General Materials Science lcsh:Microscopy lcsh:QC120-168.85 Magnetite chemistry.chemical_classification lcsh:QH201-278.5 lcsh:T Protein immobilization polymer coating Polymer 021001 nanoscience & nanotechnology 0104 chemical sciences Characterization (materials science) magnetite nanoparticles Surface coating chemistry lcsh:TA1-2040 immobilization Magnetic nanoparticles lcsh:Descriptive and experimental mechanics lcsh:Electrical engineering. Electronics. Nuclear engineering lcsh:Engineering (General). Civil engineering (General) protein 0210 nano-technology lcsh:TK1-9971 |
| Zdroj: | Materials Materials, Vol 14, Iss 248, p 248 (2021) |
| ISSN: | 1996-1944 |
| DOI: | 10.3390/ma14020248 |
| Popis: | Since their discovery, magnetic nanoparticles (MNPs) have become materials with great potential, especially considering the applications of biomedical sciences. A series of works on the preparation, characterization, and application of MNPs has shown that the biological activity of such materials depends on their size, shape, core, and shell nature. Some of the most commonly used MNPs are those based on a magnetite core. On the other hand, synthetic biopolymers are used as a protective surface coating for these nanoparticles. This review describes the advances in the field of polymer-coated MNPs for protein immobilization over the past decade. General methods of MNP preparation and protein immobilization are presented. The most extensive section of this article discusses the latest work on the use of polymer-coated MNPs for the physical and chemical immobilization of three types of proteins: enzymes, antibodies, and serum proteins. Where possible, the effectiveness of the immobilization and the activity and use of the immobilized protein are reported. Finally, the information available in the peer-reviewed literature and the application perspectives for the MNP-immobilized protein systems are summarized as well. |
| Databáze: | OpenAIRE |
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