Protriptyline: an effective agent in the treatment of the narcolepsy-cataplexy syndrome and hypersomnia
| Autor: | Hyman Pr, Schmidt Hs, Clark Rw |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Adult
Male Sleep Wake Disorders Hallucinations Pemoline Sleep REM Dibenzocycloheptenes Disorders of Excessive Somnolence Bedtime Arousal Cataplexy Medicine Humans Protriptyline Narcolepsy business.industry Sleep in non-human animals Dreams Psychiatry and Mental health Narcolepsy-Cataplexy Syndrome Anesthesia Drug Therapy Combination Sleep Stages business medicine.drug |
| Zdroj: | The American journal of psychiatry. 134(2) |
| ISSN: | 0002-953X |
| Popis: | The authors present five case reports illustrating that 10-20 mg of protriptyline in a single dose at bedtime can effectively control arousal dysfunction (sleep drunkenness and hypersomnia) and the narcolepsycataplexy syndrome without the apparent development of tolerance and without the side effects that are frequent complications of treatment with other agents. Although protriptyline was efficacious in controlling symptoms, it was found to have relatively poor REM sleep-suppressing properties. |
| Databáze: | OpenAIRE |
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