Bladder function in obstructed men – does age matter?

Autor:	Fabricio, Beltrame, Fabrizzio, Beltrame, Fabio Thadeu, Ferreira, Fabio, Lorenzetti, Mara, Dambros, Sergio, Bisogni, Miriam, Dambros
Rok vydání:	2015
Předmět:	Male Aging medicine.medical_specialty Bladder compliance Urinary system Urinary Bladder Prostatic Hyperplasia Urology Bladder capacity Lower Urinary Tract Symptoms Filling cystometry medicine Humans Aged Aged 80 and over High prevalence business.industry Urinary bladder neck obstruction Age Factors Middle Aged medicine.disease Surgery Urodynamics Correlation analysis Geriatrics and Gerontology business Bladder function Ureteral Obstruction
Zdroj:	The Aging Male. 18:143-148
ISSN:	1473-0790 1368-5538
DOI:	10.3109/13685538.2015.1025377
Popis:	The high prevalence of diseases and disabilities in the elderly will therefore impose major future challenges for governments, particularly in social security, health system and social care.Nine hundred and seventy-one men, 40 years or older referred for low urinary tract symptoms (LUTS) evaluation who underwent full urodynamic investigation, were reviewed. Urodynamic parameters were obtained, such as Uroflowmetry, those of Filling Cystometry and those of pressure flow study (PFS).Mean age was of 66.1 years old. Most the patients included in the analysis were categorized as Schafer score 2-4. Correlation analysis of uroflowmetry parameters revealed statistically significant decrease in voided volume (p = 0.013), Qmax (p = 0.023) with aging. Cystometric parameters revealed significant age-related decrease in bladder capacity (p 0.001) and bladder compliance (p = 0.004). PFS revealed significant decrease in voiding efficiency (p = 0.029), voided volume (p 0.001), Qave (p = 0.008) and Qmax (p = 0.048) with progressing age. Age subgroup analyses showed significant differences in voiding efficiency (KW, p = 0.032), voided volume (KW, p 0.001) and Qave (KW, p = 0.036).Age-related changes in voiding function might not be a result of impaired detrusor contractility or increased outflow obstruction, intrinsic causes must be suspected. Changes in the storage function of the bladder represent specific pathophysiological mechanisms influenced by aging.
Databáze:	OpenAIRE
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