Long-term follow up of gastric low-grade mucosa-associated lymphoid tissue lymphoma by endosonography emphasizing the application of a miniature ultrasound probe
| Autor: | Sheng-Shun Yang, Han-Chung Lien, Chi-Sen Chang, Wen‐Dau Chang, Sek-Kwong Poon, Hong-Zen Yeh, Guan Chou, Gran-Hum Chen |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Gastroenterology Endosonography Helicobacter Infections Stomach Neoplasms hemic and lymphatic diseases Submucosa Internal medicine medicine Gastric mucosa Humans Stage (cooking) Aged Neoplasm Staging Aged 80 and over Helicobacter pylori Hepatology biology business.industry Stomach Gastric lymphoma MALT lymphoma Lymphoma B-Cell Marginal Zone Middle Aged Anti-Ulcer Agents medicine.disease biology.organism_classification digestive system diseases Anti-Bacterial Agents Lymphoma medicine.anatomical_structure Gastric Mucosa Drug Therapy Combination Female Radiology business Omeprazole Follow-Up Studies |
| Zdroj: | Journal of Gastroenterology and Hepatology. 18:162-167 |
| ISSN: | 1440-1746 0815-9319 |
| DOI: | 10.1046/j.1440-1746.2003.02938.x |
| Popis: | Background and Aims: Endoscopic ultrasonography (EUS) is a useful tool for the evaluation of gastric wall infiltration including gastric lymphoma. The aims of this study were to characterize gastric low-grade mucosa-associated lymphoid tissue (MALT) lymphoma according to EUS findings and to evaluate the role of a miniature ultrasound probe in the long-term follow up. Methods: From January 1994 to March 2002, 20 patients were proven to have gastric low-grade MALT lymphoma. Endoscopic ultrasonography was performed with a conventional echoprobe and/or a miniature ultrasound probe for initial staging and a miniature ultrasound probe was performed during follow up. All patients positive for Helicobacter pylori received a 2-week course of omeprazole, amoxicillin and clarithromycin. Results: Helicobacter pylori infection was found in 17 (85%) patients. In all patients, H. pylori was eradicated after treatment. Initial EUS showed significantly greater wall thickness (6.1 ± 3.0 mm) in MALT lymphoma patients when compared with control (2.8 ± 0.3 mm). The infiltrative patterns included wall thickening (3.5–14.1 mm) in 18 patients: stage E-I1 in 16 (mucosa and/or submucosa), stage E-I2 in one and stage E-II in one. Complete regression of MALT lymphoma following treatment for H. pylori was noted in 14 patients, with a mean duration of 11.3 ± 9.1 months. Follow-up miniature ultrasound probe sonography showed comparative reduction in wall thickness (P |
| Databáze: | OpenAIRE |
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