Evaluation of the Relationship Between C-reactive Protein, Lactate, Procalcitonin and Albumin Levels and Procalcitonin/Albumin Ratio with SOFA and APACHE-II Scores in Emergency ICU Patients
| Autor: | Tuba Öztürk Demir, Ramazan Guven, Hilmi Kaya, Ramiz Yazici, Basar Cander, Dilek Atik, Bensu Bulut |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Icu patients critical patient lcsh:Medicine Gastroenterology Procalcitonin Internal medicine medicine crp lactate APACHE II biology business.industry C-reactive protein procalcitonin/albumin ratio lcsh:R Albumin sofa lcsh:Medical emergencies. Critical care. Intensive care. First aid lcsh:RC86-88.9 bacterial infections and mycoses apache-ii biology.protein business hormones hormone substitutes and hormone antagonists procalcitonin |
| Zdroj: | Eurasian Journal of Emergency Medicine, Vol 19, Iss 2, Pp 98-104 (2020) |
| ISSN: | 2149-6048 2149-5807 |
| Popis: | Aim:This study aimed to investigate the efficacy of C-reactive protein (CRP), lactate, procalcitonin and albumin levels and procalcitonin/ albumin ratio used as indicators of infection on mortality in critical patients admitted to the intensive care unit and their relationships with APACHE-II and SOFA scores.Materials and Methods:This study was conducted using patients’ hospital records and patient file scans. Demographic characteristics; procalcitonin, CRP, albumin and lactate levels and APACHE-II and SOFA scores were recorded. Spearman’s rank correlation was used to assess non-parametric data. ROC curve analysis was performed to determine the threshold values of blood parameters. Results: A total of 61 patients were enrolled in the present study [35 males (57.4%) and 26 females (42.6%); average age, 69.0 years]. A positive, weakly significant association was detected between APACHE-II score and procalcitonin levels. When the APACHE-II score and lactate level and procalcitonin/ albumin ratio were evaluated,Results:APACHE-II score was positively significant and weakly correlated with lactate and the procalcitonin/albumin ratio. A moderate negative correlation was found between albumin level and the APACHE-II score. The SOFA score was positively associated with both procalcitonin and lactate levels. SOFA score was positively significant and weakly correlated with the procalcitonin/albumin ratio.Conclusion:Procalcitonin, lactate and albumin levels and the procalcitonin/albumin ratio can be considered prognostic markers according to the cut-off points in terms of mortality in critically ill patients. In addition, these blood parameters were found to be useful in clinical follow-up as they are related to the APACHE-II and SOFA scoring systems used in intensive care units. |
| Databáze: | OpenAIRE |
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