CTA IN PATIENTS WITH ACUTE SUBARACHNOID HAEMORRHAGE. A comparative study with selective, digital angiography and blinded, independent review

Autor: H. K. Pedersen, Karl-Fredrik Lindegaard, I. M. Anke, Søren Jacob Bakke, Iver A. Langmoen, I. O. Skalpe, R. Sagsveen, John K. Hald, P. H. Nakstad
Rok vydání: 2001
Předmět:
Zdroj: Acta Radiologica. 42:43-49
ISSN: 1600-0455
0284-1851
DOI: 10.1034/j.1600-0455.2001.042001043.x
Popis: Purpose: Minimal- or non-invasive methods replacing intra-arterial digital subtraction angiography (IA-DSA) would be of great importance in patients suffering from acute subarachnoid haemorrhage (SAH). The aims of this study were to compare CTA with IA-DSA in patients with acute SAH, to compare CTA interpretations with those of blinded, independent reviewers and to evaluate improvement in CTA diagnostics after 1 year of experience with CTA. Material and Method: During 2 years 162 patients with SAH underwent CTA as well as IA-DSA. Independent blinded review of 77 patients was performed for 1 year. Results: Totally 144 aneurysms were demonstrated in 119 patients at IA-DSA, while 43 patients had normal intracranial arteries. Initially 131 aneurysms were detected at CTA while 2 normal, tortuous arteries were misinterpreted as aneurysms, giving a sensitivity of 91% and a specificity of 95%. At independent blinded review the observer agreement was 87% and the kappa value 0.68. Conclusion: CTA in SAH is of great value in demonstrating vascular anatomy and the exact size of an aneurysm. However, IA-DSA is still needed for diagnostic evaluation in aneurysms smaller than 5 mm in diameter, especially in those located near bony structures.
Databáze: OpenAIRE