Age-dependent effect of static magnetic field on brain tissue hydration

Autor:	Sinerik Ayrapetyan, Anna Nikoghosyan, Anush Deghoyan, Armenuhi Heqimyan
Rok vydání:	2013
Předmět:	Male Aging medicine.medical_specialty Tissue water Chemistry Biophysics Brain Water Medicine (miscellaneous) Age dependent General Medicine Brain tissue Anatomy Magnetostatics Ouabain Rats Magnetic Fields Endocrinology Internal medicine medicine Animals medicine.drug
Zdroj:	Electromagnetic Biology and Medicine. 33:58-67
ISSN:	1536-8386 1536-8378
DOI:	10.3109/15368378.2013.783852
Popis:	Age-dependent effect of Static Magnetic Field (SMF) on rats in a condition of active and inactive Na(+)/K(+) pump was studied for comparison of brain tissues hydration state changes and magnetic sensitivity. Influence of 15 min 0, 2 Tesla (T) SMF on brain tissue hydration of three aged groups of male albino rats was studied. Tyrode's physiological solution and 10(-4) M ouabain was used for intraperitoneal injections. For animal immobilization, the liquid nitrogen was used and the definition of tissue water content was performed by tissue drying method. Initial water content in brain tissues of young animals is significantly higher than in those of adult and aged ones. SMF exposure leads to decrease of water content in brain tissues of young animals and increase in brain tissues of adult and aged ones. In case of ouabain-poisoned animals, SMF gives reversal effects on brain tissue's hydration both in young and aged animals, while no significant effect on adults is observed. It is suggested that initial state of tissue hydration could play a crucial role in animal age-dependent magnetic sensitivity and the main reason for this could be age-dependent dysfunction of Na(+)/K(+) pump.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c6c5417e81296cccf1d3765f0298e7 https://doi.org/10.3109/15368378.2013.783852 Zobrazit plný text záznamu