Effect of Postoperative Oral Intake on Prognosis for Esophageal Cancer
| Autor: | Yasunori Matsuda, Harushi Osugi, Daiki Habu, Tamotsu Fujii, Chika Momoki, Shigeru Lee, Chisako Kambara, Genya Okada |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Multivariate analysis Esophageal Neoplasms medicine.medical_treatment Nutritional Status lcsh:TX341-641 Gastroenterology administration Article Eating 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Postoperative Period 030212 general & internal medicine Medical nutrition therapy Survival rate Aged Retrospective Studies Nutrition and Dietetics business.industry Hazard ratio Length of Stay Middle Aged Esophageal cancer Prognosis medicine.disease Confidence interval outcomes research/quality stomatognathic diseases Malnutrition Esophagectomy 030220 oncology & carcinogenesis esophagectomy energy intake Female business lcsh:Nutrition. Foods and food supply nutrition therapy Food Science |
| Zdroj: | Nutrients Volume 11 Issue 6 Nutrients, Vol 11, Iss 6, p 1338 (2019) |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu11061338 |
| Popis: | Background: Patients undergoing surgery for esophageal cancer are at risk of prolonged hospital stay for postoperative malnutrition. Postoperative early oral feeing is a part of the &ldquo enhanced recovery after surgery protocol&rdquo for coping with this risk. However, the usefulness of early oral intake during perioperatively is questionable. Methods: In total, 117 patients treated surgically for esophageal cancer were analyzed in the study. We assessed the oral energy sufficiency rate per nutritional requirement (oral-E/NR) at the fourth week postoperatively and classified the patients into two groups: Poor oral intake group (POI group < 25% oral-E/NR) and the control group (&ge 25% oral-E/NR). We analyzed the relationship among postoperative oral intake and prognoses. Results: The POI group had worse postoperative nutritional status and a lower survival rate than the control group. In a multivariate analysis, < 25% oral-E/NR was one of the independent factors contributing to negative outcomes postoperatively (adjusted hazard ratio: 2.70, 95% confidence interval: 1.30&ndash 5.61). Conclusions: In patients undergoing surgery for esophageal cancer, poor postoperative oral intake negatively affected not only on their postoperative nutritional status but also their overall prognosis. It is necessary to improve the adequacy of oral intake postoperatively for patients with esophageal cancer. |
| Databáze: | OpenAIRE |
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