Higher visual responses in the temporal cortex of mice
| Autor: | Nana Nishio, Manabu Abe, Katsuei Shibuki, Meiko Kawamura, Kenji Sakimura, Atsushi Aiba, Junichi Nakai, Ryuichi Hishida, Hiroaki Tsukano |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
genetic structures Photic Stimulation lcsh:Medicine Postrhinal cortex Biology Auditory cortex Article Mice 03 medical and health sciences 0302 clinical medicine Cortex (anatomy) Visual Objects Characteristic response medicine Animals lcsh:Science Visual Cortex computer.programming_language Temporal cortex Brain Mapping Multidisciplinary lcsh:R Temporal Lobe 030104 developmental biology medicine.anatomical_structure Visual cortex lcsh:Q Occipital Lobe computer Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018) Scientific Reports |
| ISSN: | 2045-2322 |
| Popis: | The visual cortex of mice is a useful model for investigating the mammalian visual system. In primates, higher visual areas are classified into two parts, the dorsal stream (“where” pathway) and ventral stream (“what” pathway). The ventral stream is known to include a part of the temporal cortex. In mice, however, some cortical areas adjacent to the primary visual area (V1) in the occipital cortex are thought to be comparable to the ventral stream in primates, although the whole picture of the mouse ventral stream has never been elucidated. We performed wide-field Ca2+ imaging in awake mice to investigate visual responses in the mouse temporal cortex, and found that the postrhinal cortex (POR), posterior to the auditory cortex (AC), and the ectorhinal and temporal association cortices (ECT), ventral to the AC, showed clear visual responses to moving visual objects. The retinotopic maps in the POR and ECT were not clearly observed, and the amplitudes of the visual responses in the POR and ECT were less sensitive to the size of the objects, compared to visual responses in the V1. In the ECT, objects of different sizes activated different subareas. These findings strongly suggest that the mouse ventral stream extends to the ECT ventral to the AC, and that it has characteristic response properties that are markedly different from the response properties in the V1. |
| Databáze: | OpenAIRE |
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