Mapping EQ-5D Utility Scores from the Incontinence Quality of Life Questionnaire among Patients with Neurogenic and Idiopathic Overactive Bladder
| Autor: | Stephen Kay, Keith Tolley, Danielle Colayco, Kristin Khalaf, Peter Anderson, Denise Globe |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Psychometrics Mean squared error Cross-sectional study I-QOL Quality of life EQ-5D Germany Sickness Impact Profile Surveys and Questionnaires Humans Medicine mapping Urinary Bladder Overactive business.industry Health Policy Fractional polynomial cross-walk real world Public Health Environmental and Occupational Health Reproducibility of Results Middle Aged Stepwise regression medicine.disease United Kingdom United States Quality-adjusted life year Cross-Sectional Studies Urinary Incontinence Overactive bladder Spain Physical therapy Female France Quality-Adjusted Life Years utility values business |
| Zdroj: | Value in Health. 16:394-402 |
| ISSN: | 1098-3015 |
| Popis: | Objectives To provide a mapping algorithm for estimating EuroQol five-dimensional (EQ-5D) questionnaire index scores from the Incontinence-specific Quality of Life questionnaire (I-QOL) based on nationally representative samples of patients with idiopathic or neurogenic overactive bladder (OAB) using EQ-5D questionnaire preference valuations based on both the UK and US general populations. Methods Analyses were conducted for 2505 patients from the Adelphi Overactive Bladder Disease Specific Programme, a cross-sectional study of patients with idiopathic or neurogenic OAB, undertaken in the United States and Europe in 2010. A range of statistical modeling techniques was used. Tenfold cross-validation techniques were used to calculate mean absolute error (MAE) and root mean squared error (RMSE) goodness-of-fit statistics. Various predictor lists, together with a method combining stepwise selection with multivariable fractional polynomial techniques to allow nonlinear relationships to feature, were pursued. Results Choice of predictors was consistent for both the UK and US EQ-5D questionnaire tariffs. For idiopathic, the best model included the I-QOL total score and age (both modeled nonlinearly.) For neurogenic, the best model was the I-QOL social embarrassment domain score modeled linearly only. Best-fit results were better in the idiopathic (n = 2351; MAE=0.10; RMSE=0.14) than in the neurogenic sample (n = 254; MAE=0.17; RMSE=0.22). Conclusions This research provides algorithms for mapping EQ-5D questionnaire index scores from the I-QOL, allowing calculation of appropriate preference-based health-related quality-of-life scores for use in cost-effectiveness analyses when only I-QOL data are available. The strongest results were for idiopathic patients, but those for neurogenic are consistent with those of other published mapping studies. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect