Atomic Force Microscope Guided SERS Spectra Observation for Au@Ag-4MBA@PVP Plasmonic Nanoparticles

Autor: Zhuyuan Wang, Libei Xu, Hui Fang, Bu Jing, Shenfei Zhong, Xiaocong Yuan, Xiuju Wu, Liu Yang
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Materials science
Silver
Finite Element Analysis
education
Pharmaceutical Science
Nanoparticle
Metal Nanoparticles
Nanotechnology
engineering.material
Microscopy
Atomic Force
Spectrum Analysis
Raman
Benzoates
Article
Analytical Chemistry
lcsh:QD241-441
symbols.namesake
lcsh:Organic chemistry
Drug Discovery
medicine
Laser power scaling
Sulfhydryl Compounds
AFM imaging
photothermal effect
Physical and Theoretical Chemistry
health care economics and organizations
chemistry.chemical_classification
Plasmonic nanoparticles
Polyvinylpyrrolidone
Organic Chemistry
Photothermal effect
technology
industry
and agriculture
Povidone
Polymer
Surface Plasmon Resonance
plasmonic nanoparticles
SERS spectra
confocal Raman spectrometer
SERS probes
chemistry
Models
Chemical
Chemistry (miscellaneous)
symbols
engineering
Molecular Medicine
Noble metal
Gold
Raman spectroscopy
medicine.drug
Zdroj: Molecules
Volume 24
Issue 20
Molecules, Vol 24, Iss 20, p 3789 (2019)
ISSN: 1420-3049
DOI: 10.3390/molecules24203789
Popis: Recently polymer encapsulated surface-enhanced-Raman-scattering (SERS) probes with internal noble metal core&ndash
shell structure has found growing applications in biomedical applications. Here we studied the SERS spectra of Au@Ag&ndash
4MBA@PVP (4MBA: 4-mercaptobenzoic acid
PVP: polyvinylpyrrolidone) plasmonic nanoparticles produced from a chemical reduction method. By linking the atomic force microscope (AFM) with the homebuilt confocal Raman spectrometer thus to use AFM images as guidance, we realized the measurement of the SERS spectra from separated nanoparticles. We investigated the cases for single nanoparticles and for dimer structures and report several observed results including SERS spectra linearly scaled with laser power, abrupt boosting and abnormal shape changing of SERS spectra for dimer structures. Based on the finite element method simulation, we explained the observed ratio of SERS signals between the dimer structure and the single nanoparticle, and attributed the observed abnormal spectra to the photothermal effect of these plasmonic nanoparticles. Our study provides valuable guidance for choosing appropriate laser power when applying similar SERS probes to image biological cells.
Databáze: OpenAIRE
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