Autologous retina transplantation for treatment of refractory double full-thickness macular hole in Alport syndrome
| Autor: | Pablo Sanjuán, Jeroni Nadal, Muhsen Samaan |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pars plana
medicine.medical_specialty genetic structures business.industry medicine.medical_treatment Vitrectomy General Medicine Fundus (eye) medicine.disease eye diseases Transplantation Ophthalmology medicine.anatomical_structure Full-thickness macular hole medicine sense organs Tamponade business Macular hole Microperimetry |
| Zdroj: | Retinal casesbrief reports. |
| ISSN: | 1937-1578 |
| Popis: | Purpose To report the structural and functional outcomes of autologous neurosensory retinal transplantation for closure of refractory double full-thickness macular hole in a patient diagnosed with Alport syndrome. Methods Patient with previous pars plana vitrectomy (PPV) and a failed macular hole surgery (ILM removal) underwent PPV and autologous neurosensory retinal flap transplantation with silicone oil tamponade. Follow-up was performed after one year. The anatomic outcomes were evaluated mainly by fundus examination, Optical coherence tomography (OCT) and microperimetry (MAIA). The functional changes were evaluated comparing best-corrected visual acuities (BCVA) preoperative and one year after surgery. Results A 35-year-old man with progressive visual loss of two years of evolution presented a double full-thickness macular hole in the left eye (LE). After retinal flap transplantation, the macular hole appeared successfully closed during the entire follow up. Integration of both retinal flaps into the surrounding retina and regeneration of the external retinal layers was observed in OCT. BCVA improved from 20/200 preoperatively to 20/80 one year postoperatively. Conclusion PPV combined with autologous neurosensory retinal flap transplantation is an effective option to achieve the anatomic closure of recurrent double full-thickness macular hole and significant visual recovery in Alport syndrome. |
| Databáze: | OpenAIRE |
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