Analysis of the genetic diversity and phylogenetic relationships of putative human papillomavirus types
| Autor: | Adriana A. Giri, Elisa Maria Bolatti, Germán R. Perez, Diego Chouhy |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Gammapapillomavirus
food.ingredient Mupapillomavirus PHYLOGENY Genome Viral Biology Alphapapillomavirus Polymerase Chain Reaction Ciencias Biológicas food Nupapillomavirus Phylogenetics Virology Betapapillomavirus Humans Papillomaviridae Phylogeny DNA Primers Genetics Genetic diversity Phylogenetic tree Papillomavirus Infections Genetic Variation PUTATIVE TYPES Oncogene Proteins Viral Sequence Analysis DNA DNA Viral HUMAN PAPILLOMAVIRUS GENETIC DIVERSITY Capsid Proteins Virología CIENCIAS NATURALES Y EXACTAS |
| Zdroj: | The Journal of general virology. 94(Pt 11) |
| ISSN: | 1465-2099 |
| Popis: | More than 170 human papillomavirus (HPV) types have been completely sequenced, curated and divided into five genera: Alphapapillomavirus, Betapapillomavirus, Gammapapillomavirus, Mupapillomavirus and Nupapillomavirus. With the application of PCR methods, hundreds of putative novel HPV types have been identified as PCR amplicons in mucosa and skin. However, at present there are no studies reporting a systematic search of the currently known L1 amplicons and their phylogenetic relationships. This survey revealed the existence of at least 202 different putative HPV types that are pending for full-genome characterization: five alphapapillomaviruses, 37 betapapillomaviruses, 159 gammapapillomaviruses and one mupapillomavirus. All potential viruses of the genera Alphapapillomavirus and Betapapillomavirus were grouped in the defined species, while 59 putative gammapapillomaviruses types were segregated in 21 unidentified putative species. These data highlight the need for progress in the identification of additional taxa of the family Papillomaviridae in order to elucidate the diversity, evolution and medical implications of these viruses. Fil: Chouhy, Diego. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Biología Molecular y Celular de Rosario; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina Fil: Bolatti, Elisa Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Biología Molecular y Celular de Rosario; Argentina Fil: Perez, Germán. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Biología Molecular y Celular de Rosario; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina Fil: Giri, Adriana Angelica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Biología Molecular y Celular de Rosario; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina |
| Databáze: | OpenAIRE |
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