Anti-MuSK-positive myasthenia gravis diagnosed during pregnancy: New challenges for an old disease
| Autor: | A. Matos, Ana Raquel Neves, Pitorra Monteiro, Isabel Santos Silva |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Receptores Proteína Tirosina Quinases medicine.medical_treatment Miastenia Gravis Disease Article Receptor tyrosine kinase Complicações na Gravidez Pregnancy Myasthenia Gravis medicine Humans Anticorpos Receptors Cholinergic Caesarean section Autoantibodies biology business.industry Obstetrics Vaginal delivery Muscles Infant Newborn Receptor Protein-Tyrosine Kinases General Medicine Delivery Obstetric medicine.disease Myasthenia gravis Pregnancy Complications Recém-Nascido Immunology biology.protein Gestation Female Antibody business |
| Popis: | Myasthenia gravis is an autoimmune disorder affecting predominantly women in their reproductive age. The course of the disease during pregnancy is unpredictable, although it is more difficult to manage earlier in the gestation. Myasthenia gravis with antibodies against the muscle-specific receptor tyrosine kinase (anti-MuSK) has been described as a subtype of disease with more localised clinical features and a poorer response to treatment than acetylcholine receptor antibody (anti-AChR)-positive patients. Few cases have been reported in pregnant women, with deliveries being performed mainly by caesarean section. We report a successful case of vaginal delivery and describe our experience providing the first review of the management of this subtype of disease during pregnancy. |
| Databáze: | OpenAIRE |
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