Buspirone/prolactin response in post head injury depression
| Autor: | Timothy G. Dinan, Mamoun Mobayed |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Personality Tests Neurocognitive Disorders Buspirone Healthy control Melancholia medicine Humans Depression (differential diagnoses) Brain Concussion Aged Psychiatric Status Rating Scales Depressive Disorder business.industry Head injury Middle Aged medicine.disease Prolactin Psychiatry and Mental health Clinical Psychology Male patient Anesthesia Serotonin medicine.symptom business medicine.drug |
| Zdroj: | Journal of affective disorders. 19(4) |
| ISSN: | 0165-0327 |
| Popis: | Fifty-five male patients who had suffered a mild head injury 11-13 months previously were investigated for evidence of depression. Eleven were diagnosed as DSM-III major depressives, nine with melancholia. Prolactin response to buspirone was examined in these patients, in eight male head-injured patients without depression and 10 age-matched male healthy controls. The prolactin response was significantly blunted in post head injury depressed patients compared to head injury non-depressed and healthy control groups. We suggest that these differences may be due to altered serotonin functioning post head injury. |
| Databáze: | OpenAIRE |
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