Myopericytoma in an unusual location
| Autor: | Mariana Catalina De Anda-Juárez, Sonia Toussaint-Caire, Ana Laura Ramirez Teran, Verónica Fonte-Avalos, Carlos Ortiz-Hidalgo, Ma Elisa Vega-Memije, León Felipe Ruiz-Arriaga |
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| Rok vydání: | 2018 |
| Předmět: |
Pathology
medicine.medical_specialty Skin Neoplasms Necrosis Proliferation index Myofibroma myopericytoma myopericytic tumor soft-tissue tumor Myopericytoma Dermatology Eye 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Eosinophilic medicine Humans business.industry General Medicine Middle Aged medicine.disease Left eye 030220 oncology & carcinogenesis Immunohistochemistry Female Desmin Facial Neoplasms Neoplasm Recurrence Local medicine.symptom Pericytes business Myofibroblast |
| Zdroj: | Ruiz-Arriaga, Leon Felipe; Ramirez Teran, Ana Laura; Ortiz-Hidalgo, Carlos; Fonte-Avalos, Veronica; Toussaint-Caire, Sonia; Vega-Memije, Ma Elisa; et al.(2018). Myopericytoma in an unusual location. Dermatology Online Journal, 24(4). Retrieved from: http://www.escholarship.org/uc/item/5z02t0dk |
| ISSN: | 1087-2108 |
| DOI: | 10.5070/d3244039361 |
| Popis: | Myopericytoma is a soft-tissue tumor of perivascular cells (pericytes). It is slow-growing, usually asymptomatic, and generally benign, although a malignant variant has been described. The etiology is unknown, but it has been associated with local trauma. The most common location is on the distal extremities. Histologically, it is characterized by a well-circumscribed, non-encapsulated proliferation of spindle shaped cells similar to myofibroblasts with oval nuclei and eosinophilic cytoplasm, arranged in perivascular concentric rings. There are few mitoses and no necrosis is reported. The immunohistochemical analysis is positive for smooth muscle actin and negative or weakly positive for desmin. A low Ki-67 proliferation index is typical. Treatment is surgical excision with free margins. Recurrences after adequate excision are uncommon. We describe a 48-year-old woman with a myopericytoma in an unusual location (next to the inner corner of her left eye) who was treated with surgical excision; there has been no recurrence after 5 years of follow up. |
| Databáze: | OpenAIRE |
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