Immunofluorescent localization of Staphylococcos aureus antigen in acute bacterial endocarditis nephritis
Autor: | Moonahm Yum, Lawrence J. Wheat, Douglas R. Maxwell, Joshua L. Edwards |
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Rok vydání: | 1978 |
Předmět: |
Male
Pathology medicine.medical_specialty Antigen-Antibody Complex Staphylococcus aureus Kidney Glomerulus Fluorescent Antibody Technique Chick Embryo Immunofluorescence medicine.disease_cause Pathogenesis Glomerulonephritis Antigen medicine Animals Humans Antigens Bacterial medicine.diagnostic_test biology urogenital system business.industry Immune Sera General Medicine Endocarditis Bacterial Staphylococcal Infections medicine.disease Antibodies Bacterial Microscopy Electron Acute Disease biology.protein Antibody business Nephritis |
Zdroj: | American journal of clinical pathology. 70(5) |
ISSN: | 0002-9173 |
Popis: | A 75-year-old man with Staphylococcus aureus endocarditis in whom acute diffuse proliferative glomerulonephritis developed is described. The light- and electron-microscopic changes of the glomeruli in this case were identical to those of acute poststreptococcal glomerulonephritis. Immunofluorescence revealed deposition of immunoglobulins and complement in the glomeruli. In addition, bacterial antigenic material was demonstrated in the glomeruli by indirect immunofluorescence. These observations further support the hypothesis of an immune-complex pathogenesis in this form of glomerulonephritis. |
Databáze: | OpenAIRE |
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