Free radicals, atherosclerosis, ageing and related dysmetabolic pathologies: biochemical and molecular aspects
| Autor: | F Fabris, A Giuliani, C Scarafiotti, B Cestaro |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Blood lipoprotein
Cancer Research medicine.medical_specialty Aging Free Radicals Epidemiology Arteriosclerosis Cell Survival Radical Risk Assessment Lipid peroxidation Increased lipid chemistry.chemical_compound Adenosine Triphosphate Metabolic Diseases Internal medicine medicine Humans Molecular Biology Aged Lipid peroxide Cell Membrane Public Health Environmental and Occupational Health Endocrinology Membrane medicine.anatomical_structure Oncology chemistry Ageing Blood Vessels lipids (amino acids peptides and proteins) Blood vessel |
| Zdroj: | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). 6 |
| ISSN: | 0959-8278 |
| Popis: | In human ageing and with many pathologies correlated to the senile functional decay of cells, membrane damage often occurs in some organ or tissue, which provokes lipid peroxidation in the membrane and accelerates the disorder in structure and function of the membrane. When lipid peroxides accumulate sufficiently, they leak from the organ or tissue into the bloodstream and increase the lipid peroxide level in blood lipoproteins. The increased lipid peroxides in the blood attack the blood vessel and promote atherogenesis. This paper describes the possible involvement of free radicals in this damage, both to tissues and to blood vessels, which contributes to the senile functional decay of the tissues. |
| Databáze: | OpenAIRE |
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