Differences between Coronary Hyperresponsiveness to Ergonovine and Vasospastic Angina
| Autor: | Shinzato Yuzuru, Sunagawa Osahiko, Tomori Masayuki, Touma Takashi, Fukiyama Koshiro |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Angina Pectoris
Variant Male medicine.medical_specialty Ischemia Coronary Vasospasm Coronary Artery Disease Impaired glucose tolerance Sex Factors Internal medicine medicine Humans Ergometrine Ergonovine Coronary atherosclerosis Aged Vascular disease business.industry Smoking Vasospasm Odds ratio Glucose Tolerance Test Middle Aged medicine.disease Coronary Vessels Anesthesia Cardiology Female Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Japanese Heart Journal. 41:257-268 |
| ISSN: | 1348-673X 0021-4868 |
| Popis: | The objective of the present study was to investigate the differences between coronary hyperresponsiveness without ischemia and vasospastic angina in an ergonovine provocation test using multivariate analysis. We have sometimes experienced a more than 50% narrowing response of vascular diameter without ischemia in a coronary response to ergonovine. We studied 107 patients with less than 50% stenosis in a coronary arteriogram. Their vascular responses to ergonovine were measured and the patients were divided into three groups, as follows: Group 1 had 50% or less vascular narrowing response without ischemia; Group 2 had a vascular hyperresponsiveness of more than 50% narrowing response without ischemia; and Group 3 experienced a hyperresponsiveness with ischemia. The degree of coronary response was found to be related to smoking, inpaired glucose tolerance (IGT) and the Gensini score by multiple regression analysis. A multiple logistic analysis revealed that the Gensini score and smoking were significant predictive factors for Group 3 (odds ratio: 1.20 and 8.97). The only factor different between Group 2 and Group 1 was gender. The coronary hyperresponsiveness to ergonovine without ischemia differs from vasospastic angina in the degree of coronary atherosclerosis and smoking habits. The patients with hyperresponsiveness had similar characteristics to those with atypical chest pain rather than vasospastic angina, except for a gender difference. |
| Databáze: | OpenAIRE |
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