Brainstem Hyperexcitability During Cataplexy
| Autor: | Howard W. Sander, Christine Quinto, Sudhansu Chokroverty, Ingela Danielsson, Charles Gellido |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Cataplexy Lateral hypothalamus Physiology Withdrawal reflex Physiology (medical) Reflex medicine Humans Corneal reflex Aged Blinking business.industry Electroencephalography medicine.disease Electric Stimulation nervous system Neurology Disinhibition Sleep Stages Neurology (clinical) Brainstem Tibial Nerve medicine.symptom business Neuroscience Jaw jerk reflex Brain Stem Narcolepsy |
| Zdroj: | Journal of Clinical Neurophysiology. 22:275-278 |
| ISSN: | 0736-0258 |
| Popis: | The exact cause of narcolepsy-cataplexy syndrome remains unclear; however, the recent discovery of hypocretin deficiency in the lateral hypothalamus of narcoleptic patients has increased our understanding of its etiology. The authors performed masseter reflex, tibial F response, and blink reflex excitability studies during and between attacks in a 66-year-old man with status cataplecticus. Masseter reflex and F responses were inhibited while the blink reflex R2 component was enhanced during attacks, suggesting either hyperexcitability or disinhibition of pontine and/or medullary interneurons but hypoexcitability of pontine and spinal motor neurons during cataplexy. |
| Databáze: | OpenAIRE |
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