Efeito do extrato da casca de Syzygium cumini sobre a atividade da acetilcolinesterase em ratos normais e diabéticos

Autor: Maísa Corrêa, Andreane Filappi, Deila Rosély Schossler, Adriane Cismoski da Silva, Maria Rosa Chitolina Schetinger, Wellington de Abreu Gonzaga, Gilberto Inácio Lunkes, Vera Maria Morsch, Danívia Prestes, Marcelo Cecim, Cinthia M. Mazzanti
Jazyk: portugalština
Rok vydání: 2004
Předmět:
Zdroj: Ciência Rural v.34 n.3 2004
Ciência Rural
Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
Popis: The present study verified the efficiency of the bark ethanol extract of Syzygium cumini on the cholinergic system of normal and alloxan induced diabetic rats. Thirty-nine female rats were divided in control (C), treated with Syzygium cumini (TS), diabetic (D) and diabetic treated with Syzygium cumini (DS). The activity of acetylcholinesterase (AChE) was analyzed in the following cerebral structures: cerebellum, cortex, striatum and hippocampus. The extract of the bark of Syzygium cumini in the dose of 1g.kg-1 was administered orally daily for a period of thirty days. After this period the extract inhibited the activity of the AChE in the cerebellum and cerebral cortex of the rats in the DS group (P
Databáze: OpenAIRE