Potentially Inappropriate Medication Use in Older Adults With Mild Cognitive Impairment
| Autor: | Kristine Yaffe, Cynthia Barton, Andrea Weston, Andrea M. Weinstein |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
Aging medicine.medical_specialty Potentially Inappropriate Medication List Cross-sectional study Beers Criteria Anticholinergic agents Affect (psychology) California Risk Factors hemic and lymphatic diseases Internal medicine Prevalence Humans Medication Errors Medicine Myocardial infarction Psychiatry Aged Retrospective Studies business.industry Retrospective cohort study Cognition Prognosis medicine.disease Cross-Sectional Studies Journal of Gerontology: MEDICAL SCIENCES Female Geriatrics and Gerontology Cognition Disorders business Follow-Up Studies |
| Zdroj: | The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. :318-321 |
| ISSN: | 1758-535X 1079-5006 |
| Popis: | Background. Patients with mild cognitive impairment (MCI) may be especially vulnerable to the side effects of potentially inappropriate medications (PIMs), especially those that impair cognition. Methods. We conducted a cross-sectional study to determine the prevalence of PIM use among 689 patients with MCI. We used the 2003 Beers Criteria for cognitive impairment to identify PIMs. We then determined if certain patients were more likely to use PIMs. Results. There were 143 (20.8%) patients with MCI taking a PIM: 108 (15.7%) patients were taking one PIM and 35 (5.1%) patients were taking two or more PIMs. The most common PIMs were anticholinergics (35.7%) and benzodiazepines (31.5%). Patients were more likely to be taking PIMs if they were women and were taking a greater number of medications and less likely if they had a history of myocardial infarction. Conclusions. Patients with MCI are frequently taking PIMs that may negatively affect cognition. Future research is needed to assess whether cognitive impairment symptoms are improved if PIM use is reduced. |
| Databáze: | OpenAIRE |
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