Antibiotic susceptibilities, serotypes and auxotypes of Neisseria gonorrhoeae isolated in New Zealand
| Autor: | H G Davies, M S Brett, H M Heffernan, J R Blockley |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Serotype
biology medicine.drug_class Tetracycline Antibiotics Drug Resistance Microbial Dermatology biology.organism_classification medicine.disease_cause Virology Neisseria gonorrhoeae Microbiology Penicillin Infectious Diseases Antibiotic resistance Prevalence medicine Animals Neisseriaceae Serotyping Bacteria New Zealand Research Article medicine.drug |
| Zdroj: | Sexually Transmitted Infections. 68:321-324 |
| ISSN: | 1368-4973 |
| DOI: | 10.1136/sti.68.5.321 |
| Popis: | OBJECTIVE--The aim of the study was to determine the distribution of auxotypes and serotypes and the prevalence of antibiotic resistance among New Zealand isolates of Neisseria gonorrhoeae. MATERIALS AND METHODS--A total of 486 gonococci isolated in 1988 were auxotyped, serotyped, and tested for susceptibilities to ten antibiotics. RESULTS--The gonococci were susceptible to all the antibiotics tested except penicillin and tetracycline. Eleven (2.2%) produced beta-lactamase, one (0.2%) showed chromosomal penicillin resistance, and 18 (3.7%) were resistant to a low-level of tetracycline. Most of the gonococci belonged to six auxotypes. The three predominant auxotypes were arginine-requiring (Arg-), non-requiring (NR), and arginine, hypoxanthine, uracil-requiring (AHU-). The majority of the isolates belonged to serogroup IB and to six serovars. The most prevalent serovars were IB-3 and IB-1. There was an association between penicillin susceptibility and auxotype or serovar among non-penicillinase producing N. gonorrhoeae (PPNG) isolates. CONCLUSIONS--Antibiotic resistance, including penicillin resistance, remains uncommon among gonococci in New Zealand. Baselines have been established for future epidemiological studies using both auxotyping and serotyping. |
| Databáze: | OpenAIRE |
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